AstraZeneca PLC (AZN) vs Stryker Corporation (SYK)

AZN leads on 17 of 17 compared metrics.

A side-by-side comparison of AstraZeneca PLC and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 12, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — AZN vs SYK

growth of $100 · last 30y
AZN +658.3%SYK +5726.5%SYK compounded faster
Log scale — wide-divergence pair
101001k10kStart $100200120062011201620212026$758$5,827
AZN SYK

AZN vs SYK: by the numbers

  • AZN is the larger company ($133.07B vs $126.42B market cap).
  • AZN trades at the lower earnings multiple (12.92 vs 38.17 P/E).
  • AZN converts more revenue to profit (17.19% vs 13.21% net margin).
  • AZN grew revenue faster over the past five years (16.99% vs 11.42% CAGR).
  • AZN pays the higher dividend yield (2.53% vs 1.07%).

Which is better, AZN or SYK?

Metric tally: AZN 17 · SYK 0

It depends on what you're optimizing for:

ValueAZN(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeAZN(higher dividend yield)
QualityAZN(higher ROIC)

Metrics side by side

Valuation

MetricAZNSYK
P/E ratio12.9238.17
Forward P/E16.7522.01
P/S ratio2.225.04
P/B ratio2.835.55
PEG ratio0.295.16
EV / EBITDA7.9621.06
FCF yield6.02%3.59%

Profitability

MetricAZNSYK
Gross margin81.68%63.67%
Operating margin23.69%21.34%
Net margin17.19%13.21%
ROE21.95%14.52%
ROIC13.03%8.53%

Dividends

MetricAZNSYK
Dividend yield2.53%1.07%
Payout ratio32.88%41.46%

Growth (annualized)

MetricAZNSYK
Revenue CAGR (5Y)16.99%11.42%
EPS CAGR (5Y)22.02%14.79%
FCF CAGR (5Y)15.68%11.01%
Total return CAGR (5Y)9.97%5.60%

Frequently asked

Which is better, AZN or SYK?
It depends on your goal. value: AZN (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: AZN (higher dividend yield); quality: AZN (higher ROIC). Across all compared metrics, AZN leads 17 to 0.
Is AZN or SYK cheaper?
On trailing earnings, AZN is cheaper: AZN trades at a 12.92 P/E and SYK at 38.17.
Which has grown faster, AZN or SYK?
Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus SYK at 11.42%.
Does AZN or SYK pay a bigger dividend?
AZN yields 2.53% and SYK yields 1.07% based on trailing dividends and the latest price.
Is AZN or SYK more profitable?
AZN runs the higher net margin — AZN at 17.19% versus SYK at 13.21%.
Which has been the better investment, AZN or SYK?
Over the past 10-year, AZN delivered the higher annualized total return — AZN at 14.53% versus SYK at 11.65%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 12, 2026.