AstraZeneca PLC (AZN) vs Stryker Corporation (SYK)
AZN leads on 17 of 17 compared metrics.
A side-by-side comparison of AstraZeneca PLC and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 12, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — AZN vs SYK
growth of $100 · last 30yAZN +658.3%SYK +5726.5%SYK compounded faster
Log scale — wide-divergence pair
AZN SYK
AZN vs SYK: by the numbers
- •AZN is the larger company ($133.07B vs $126.42B market cap).
- •AZN trades at the lower earnings multiple (12.92 vs 38.17 P/E).
- •AZN converts more revenue to profit (17.19% vs 13.21% net margin).
- •AZN grew revenue faster over the past five years (16.99% vs 11.42% CAGR).
- •AZN pays the higher dividend yield (2.53% vs 1.07%).
Which is better, AZN or SYK?
Metric tally: AZN 17 · SYK 0It depends on what you're optimizing for:
ValueAZN(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeAZN(higher dividend yield)
QualityAZN(higher ROIC)
Metrics side by side
Valuation
| Metric | AZN | SYK |
|---|---|---|
| P/E ratio | 12.92● | 38.17 |
| Forward P/E | 16.75● | 22.01 |
| P/S ratio | 2.22● | 5.04 |
| P/B ratio | 2.83● | 5.55 |
| PEG ratio | 0.29● | 5.16 |
| EV / EBITDA | 7.96● | 21.06 |
| FCF yield | 6.02%● | 3.59% |
Profitability
| Metric | AZN | SYK |
|---|---|---|
| Gross margin | 81.68%● | 63.67% |
| Operating margin | 23.69%● | 21.34% |
| Net margin | 17.19%● | 13.21% |
| ROE | 21.95%● | 14.52% |
| ROIC | 13.03%● | 8.53% |
Dividends
| Metric | AZN | SYK |
|---|---|---|
| Dividend yield | 2.53%● | 1.07% |
| Payout ratio | 32.88% | 41.46% |
Growth (annualized)
| Metric | AZN | SYK |
|---|---|---|
| Revenue CAGR (5Y) | 16.99%● | 11.42% |
| EPS CAGR (5Y) | 22.02%● | 14.79% |
| FCF CAGR (5Y) | 15.68%● | 11.01% |
| Total return CAGR (5Y) | 9.97%● | 5.60% |
Frequently asked
- Which is better, AZN or SYK?
- It depends on your goal. value: AZN (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: AZN (higher dividend yield); quality: AZN (higher ROIC). Across all compared metrics, AZN leads 17 to 0.
- Is AZN or SYK cheaper?
- On trailing earnings, AZN is cheaper: AZN trades at a 12.92 P/E and SYK at 38.17.
- Which has grown faster, AZN or SYK?
- Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus SYK at 11.42%.
- Does AZN or SYK pay a bigger dividend?
- AZN yields 2.53% and SYK yields 1.07% based on trailing dividends and the latest price.
- Is AZN or SYK more profitable?
- AZN runs the higher net margin — AZN at 17.19% versus SYK at 13.21%.
- Which has been the better investment, AZN or SYK?
- Over the past 10-year, AZN delivered the higher annualized total return — AZN at 14.53% versus SYK at 11.65%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioStryker P/E ratioAstraZeneca dividend yieldStryker dividend yieldAstraZeneca ROEStryker ROEAstraZeneca operating marginStryker operating marginAstraZeneca revenue growthStryker revenue growthAstraZeneca free cash flowStryker free cash flow
AstraZeneca & Stryker appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 12, 2026.