Is AMGN or SYK cheaper?

On trailing earnings, AMGN is cheaper: AMGN trades at a 24.21 P/E and SYK at 34.85.

Which has grown faster, AMGN or SYK?

Over the past five years, SYK grew revenue faster — AMGN at a 8.15% CAGR versus SYK at 11.42%.

Does AMGN or SYK pay a bigger dividend?

AMGN yields 2.82% and SYK yields 1.14% based on trailing dividends and the latest price.

Is AMGN or SYK more profitable?

AMGN runs the higher net margin — AMGN at 20.95% versus SYK at 13.21%.

Which has been the better investment, AMGN or SYK?

Over the past 10-year, AMGN delivered the higher annualized total return — AMGN at 12.07% versus SYK at 11.39%. Past performance doesn't predict future results.

Amgen Inc. (AMGN) vs Stryker Corporation (SYK)

AMGN leads on 12 of 17 compared metrics.

A side-by-side comparison of Amgen Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 17, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — AMGN vs SYK

growth of $100 · last 30y

AMGN +2239.8%SYK +4649.8%SYK compounded faster

AMGN SYK

AMGN vs SYK: by the numbers

•AMGN is the larger company ($187.59B vs $115.45B market cap).
•AMGN trades at the lower earnings multiple (24.21 vs 34.85 P/E).
•AMGN converts more revenue to profit (20.95% vs 13.21% net margin).
•SYK grew revenue faster over the past five years (11.42% vs 8.15% CAGR).
•AMGN pays the higher dividend yield (2.82% vs 1.14%).

Which is better, AMGN or SYK?

Metric tally: AMGN 12 · SYK 5

It depends on what you're optimizing for:

ValueAMGN(lower P/E)

GrowthSYK(faster 5Y revenue CAGR)

IncomeAMGN(higher dividend yield)

QualityAMGN(higher ROIC)

Metrics side by side

Valuation

Metric	AMGN	SYK
P/E ratio	24.21●	34.85
Forward P/E	14.83●	18.00
P/S ratio	5.08	4.61●
P/B ratio	20.59	5.07●
PEG ratio	0.26●	5.16
EV / EBITDA	14.05●	20.89
FCF yield	4.54%●	3.93%

Profitability

Metric	AMGN	SYK
Gross margin	71.46%●	63.67%
Operating margin	31.63%●	21.34%
Net margin	20.95%●	13.21%
ROE	84.87%●	14.52%
ROIC	13.16%●	8.53%

Dividends

Metric	AMGN	SYK
Dividend yield	2.82%●	1.14%
Payout ratio	68.39%	40.52%

Growth (annualized)

Metric	AMGN	SYK
Revenue CAGR (5Y)	8.15%	11.42%●
EPS CAGR (5Y)	2.94%	14.79%●
FCF CAGR (5Y)	-2.66%	11.01%●
Total return CAGR (5Y)	11.05%●	4.08%

Frequently asked

Which is better, AMGN or SYK?: It depends on your goal. value: AMGN (lower P/E); growth: SYK (faster 5Y revenue CAGR); income: AMGN (higher dividend yield); quality: AMGN (higher ROIC). Across all compared metrics, AMGN leads 12 to 5.
Is AMGN or SYK cheaper?: On trailing earnings, AMGN is cheaper: AMGN trades at a 24.21 P/E and SYK at 34.85.
Which has grown faster, AMGN or SYK?: Over the past five years, SYK grew revenue faster — AMGN at a 8.15% CAGR versus SYK at 11.42%.
Does AMGN or SYK pay a bigger dividend?: AMGN yields 2.82% and SYK yields 1.14% based on trailing dividends and the latest price.
Is AMGN or SYK more profitable?: AMGN runs the higher net margin — AMGN at 20.95% versus SYK at 13.21%.
Which has been the better investment, AMGN or SYK?: Over the past 10-year, AMGN delivered the higher annualized total return — AMGN at 12.07% versus SYK at 11.39%. Past performance doesn't predict future results.

Go deeper

Full AMGN analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Amgen P/E ratio Stryker P/E ratio Amgen dividend yield Stryker dividend yield Amgen ROE Stryker ROE Amgen operating margin Stryker operating margin Amgen revenue growth Stryker revenue growth Amgen free cash flow Stryker free cash flow

Amgen & Stryker appear in these rankings

Highest Dividend Yield Stocks Highest ROE Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 17, 2026.