Is ALNY or EW cheaper?

On trailing earnings, EW is cheaper: ALNY trades at a 63.53 P/E and EW at 45.60.

Which has grown faster, ALNY or EW?

Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus EW at 7.10%.

Is ALNY or EW more profitable?

EW runs the higher net margin — ALNY at 13.46% versus EW at 17.34%.

Which has been the better investment, ALNY or EW?

Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.31% versus EW at 9.15%. Past performance doesn't predict future results.

Alnylam Pharmaceuticals, Inc. (ALNY) vs Edwards Lifesciences Corporation (EW)

EW leads on 8 of 14 compared metrics.

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Edwards Lifesciences Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 20, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

ALNY

Alnylam Pharmaceuticals, Inc.

$36.40B

$272.67HealthcareDelayed quote: Jul 20, 2026, 4:00 PM EDT

Edwards Lifesciences Corporation

$48.94B

$85.00HealthcareDelayed quote: Jul 20, 2026, 4:00 PM EDT

Total return — ALNY vs EW

growth of $100 · dividends reinvested · last 22y

ALNY +4444.9%EW +2783.8%ALNY compounded faster

ALNY EW

ALNY vs EW: by the numbers

•EW is the larger company ($48.94B vs $36.40B market cap).
•EW trades at the lower earnings multiple (45.60 vs 63.53 P/E).
•EW converts more revenue to profit (17.34% vs 13.46% net margin).
•ALNY grew revenue faster over the past five years (49.67% vs 7.10% CAGR).

Which is better, ALNY or EW?

Metric tally: ALNY 6 · EW 8

It depends on what you're optimizing for:

ValueEW(lower P/E)

GrowthALNY(faster 5Y revenue CAGR)

QualityALNY(higher ROIC)

Metrics side by side

Valuation

Metric	ALNY	EW
P/E ratio	63.53	45.60●
Forward P/E	35.91	28.49●
P/S ratio	8.62	7.90●
P/B ratio	34.38	4.82●
PEG ratio	—	6.64
EV / EBITDA	45.27	25.26●
FCF yield	1.73%	2.19%●

Profitability

Metric	ALNY	EW
Gross margin	80.89%●	78.01%
Operating margin	17.54%	27.62%●
Net margin	13.46%	17.34%●
ROE	53.68%●	10.58%
ROIC	13.74%●	11.40%

Growth (annualized)

Metric	ALNY	EW
Revenue CAGR (5Y)	49.67%●	7.10%
EPS CAGR (5Y)	—	6.87%
FCF CAGR (5Y)	14.35%●	8.74%
Total return CAGR (5Y)	8.32%●	-4.34%

Frequently asked

Which is better, ALNY or EW?: It depends on your goal. value: EW (lower P/E); growth: ALNY (faster 5Y revenue CAGR); quality: ALNY (higher ROIC). Across all compared metrics, EW leads 8 to 6.
Is ALNY or EW cheaper?: On trailing earnings, EW is cheaper: ALNY trades at a 63.53 P/E and EW at 45.60.
Which has grown faster, ALNY or EW?: Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus EW at 7.10%.
Is ALNY or EW more profitable?: EW runs the higher net margin — ALNY at 13.46% versus EW at 17.34%.
Which has been the better investment, ALNY or EW?: Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.31% versus EW at 9.15%. Past performance doesn't predict future results.

Go deeper

Full ALNY analysis Full EW analysis Interactive comparison tool

Dig into the metrics

Alnylam Pharmaceuticals P/E ratio Edwards Lifesciences P/E ratio Alnylam Pharmaceuticals dividend yield Edwards Lifesciences dividend yield Alnylam Pharmaceuticals ROE Edwards Lifesciences ROE Alnylam Pharmaceuticals operating margin Edwards Lifesciences operating margin Alnylam Pharmaceuticals revenue growth Edwards Lifesciences revenue growth Alnylam Pharmaceuticals free cash flow Edwards Lifesciences free cash flow

Alnylam Pharmaceuticals & Edwards Lifesciences appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Best 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 20, 2026.